A related study by the University of Coimbra in Portugal found that caffeine and other natural substances that can be found in coffee may decrease the severity of non-alcoholic fatty liver disease (NAFLD) in people who are situation of overweight with type 2 diabetes.
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This is a collective term for liver disease caused by an accumulation of fat in the organ. They can lead to liver fibrosis, which can lead to cirrhosis and liver cancer. NAFLD is not a result of excessive alcohol consumption but rather a combination of factors such as an unhealthy lifestyle, poor exercise and an unbalanced diet.
Study participants who consumed more coffee were shown to have healthier livers, as well as exhibiting a lower risk of having liver fibrosis. Other substances found in decaffeinated coffee could be linked to less fatty livers.
The researchers followed 156 volunteers who bordered on morbid obesity, all in middle age. About 98 of those had type 2 diabetes. All participants submitted urine samples every 24 hours to analyze the metabolites found in caffeine and decaffeinated coffee.
Thus, it became clear that caffeine consumption may be related to a decrease in liver fibrosis in non-alcoholic fatty liver diseases and other chronic liver diseases.
Other components found in coffee, such as polyphenols, could be associated with a decrease in oxidative stress in the liver, decreased risk of fibrosis and glucose homeostasis, both in overweight individuals and in others. All the factors mentioned collaborate with the reduction of severity found in patients with type 2 diabetes.
According to the lead author of the study:
“Due to changes in modern diet and lifestyle, obesity rates are increasing, and the incidence of type 2 diabetes and liver disease non-alcoholic fatty acids are increasing, which can eventually lead to more serious and irreversible conditions, causing problems in the health systems. health. Our research is the first to demonstrate that higher cumulative levels of caffeine and decaffeinated metabolites in the urine are related to lower NAFLD severity in overweight people with diabetes type 2″.
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