Study reveals that Pfizer's oral drug and Novo Nordisk's Ozempic injection provide similar results in weight loss. The results, coming from phase 2 clinical trials, were released at a medical conference late last year and have now been peer-reviewed and published by JAMA Network.
The study did not directly compare the Pfizer drug to Ozempic or other weight-loss drugs. However, the results suggest a comparable effectiveness between the two most recent treatments on the market, which could be a new alternative. Follow the thread!
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Pfizer's oral medication may help you lose weight
A study by Pfizer involved 411 adults with type 2 diabetes who were given the company's oral drug, called danuglipron, twice a day.
The results showed a significant reduction in the patients' body weight after using either the 120 milligram or 80 milligram versions of the medication, which lasted for a period of 16 weeks. These findings suggest that the drug may be effective in promoting weight loss in patients with type 2 diabetes.
These results indicate that Pfizer's oral medication may offer an advantageous alternative to the need for frequent injections, as in the case of Ozempic.
Although the dosages of Ozempic and danulglipron are different, the results suggest that Pfizer's drug may be equally effective in weight loss. This offers patients an additional option for weight loss treatment, expanding the therapeutic possibilities available on the market.
How do weight loss drugs work?
Danuglipron, Wegovy and Ozempic are all endowed with glucagon-like peptide-1, belonging to the class of drugs known as GLP-1 agonists.
These drugs mimic the action of GLP-1, a hormone naturally produced in the gut that plays a crucial role in controlling appetite and regulating blood glucose levels.
By mimicking GLP-1, these drugs activate GLP-1 receptors in the brain and pancreas. In the brain, they help reduce appetite and promote feelings of fullness, which can lead to a reduction in food intake.
In the pancreas, they stimulate the release of insulin, a hormone responsible for controlling blood glucose levels, thus helping to lower blood sugar levels.
These drugs are often prescribed for the treatment of obesity and type 2 diabetes, as they have been shown to be effective in losing weight and controlling blood glucose levels.
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