O paracetamol, one of the most consumed medicines in the world, hides intriguing secrets and potential dangers that few know.
The ease of access to this medicine, freely available in pharmacies without the need for a prescription, has made it a controversial protagonist in many people's lives.
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But, far beyond its popularity, the drug holds many mysteries that leave scientists baffled to this day. Understand more below!
A dose of statistics
Impressive data reveal the extent of paracetamol's presence in people's lives. Us U.S, for example, it is estimated that around 49,000 tons of the drug are sold annually, equivalent to 298 pills per American every 12 months.
In the UK, the average is 70 units per person over the same period. A remedy that has become part of everyday life, ready to fight common pains and fevers.
Interestingly, paracetamol, despite being known for over a century, still intrigues scientists as to how it works to reduce pain and lower fever in the body.
Experts believe that it can influence the central nervous system and peripheral regions with inflammation. However, uncertainty persists.
(Image: Getty Images/Reproduction)
Although it is one of the most widely consumed drugs, evidence on the effectiveness of acetaminophen varies. Studies reveal that, in some situations, such as low back pain, its effect is not superior to that of placebo.
The Cochrane Institute, which reviews evidence of treatments, found that, for some pain, paracetamol also does not overcome the effect of substances without therapeutic properties.
However, it is important to note that it can still be effective in cases such as acute migraines and pain. post childbirth and post-surgical.
The Dangerous Side of Success
The accessibility of paracetamol and the lack of guidance on consumption limits resulted in a serious problem: overdose. Medication is the main cause of liver failure in countries like USA and UK.
The liver metabolizes paracetamol, but in excessive doses a toxic substance is produced. This can lead to acute liver failure and even death.
In countries like the US, paracetamol overdoses were the leading cause of acute liver failure at one point. Therefore, adequate dosage is essential to avoid complications.
Health bodies recommend a limit of 4 grams per day for adults. However, many combine paracetamol with other substances, which can lead to accidental consumption above the limit.
The liver cannot neutralize the toxic substance in large amounts, resulting in serious problems.
In addition to the physical effects, paracetamol can have impacts on social relationships. One study revealed that volunteers who took paracetamol demonstrated a reduced ability to feel empathy to a lesser or greater degree. This raises questions about how this drug affects social behaviors and emotions.
However, the results are experimental and still do not fully reflect the complex reality of social interactions.
A remedy from the past for today's challenges
Acetaminophen's success can be attributed to factors such as historical reliance on medications, broad indications, affordability, and the lack of alternatives for immediate pain relief.
The massive use of pain medicine reflects a society that seeks quick solutions. However, the complexity of relief goes beyond a pill and may require broader efforts and treatments.
In a world of multiple stresses, pain is one of the most impactful conditions, and paracetamol it is an important option, but its use must be cautious and always guided by health professionals.
Amidst the mysteries and challenges, the remedy that tackles pain also reminds us of the importance of a more comprehensive and thoughtful approach to well-being.