A promising breakthrough in dentistry is about to be tested on humans. A team of Japanese scientists has developed a drug composed of monoclonal antibodies that stimulates the growth of new teeth.
After successful testing in rodent animals, the researchers plan to start clinical trials in July 2024. If all goes as expected, this treatment could be available internationally by 2030.
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Emergence of the idea and first steps of the research
The idea of growing new teeth has been the dream of many dentists, and is now one step closer to reality.
The researchers discovered that a specific gene limits tooth growth and developed a monoclonal antibody to block this action.
Tests on animals have shown promising results, leading to the expectation that the drug will have the same effectiveness in humans.
The drug will be aimed primarily at patients with anodontia, a congenital condition in which one or more teeth fail to develop in the mouth.
This condition is currently treated with dental implants, but the new treatment offers a less invasive alternative.
Human trials are expected to begin next year. The clinical research phase will be carried out in the Japan, and the drug is expected to be safe and effective, paving the way for its clinical use in the near future.
What researchers expect from this treatment
The first group to use this medication will be children aged 2 to 6 years with anodontia. This age group represents one of the population groups most affected by this condition, which will benefit from a natural and innovative treatment option.
In the future, it is expected that the therapy will be expanded to people who have lost teeth for various reasons, such as cavities not treated.
In that sense, it could transform the traditional approach to dental implants and dentures, revolutionizing dental care.
If successful, the drug could open doors to tooth regeneration and offer a bold solution for people facing dental problems.
The future of dentistry is getting brighter and the possibility of growing new teeth could become a reality in the not-too-distant future.