Osmosis in Medicine – Hemodialysis. Osmosis and hemodialysis

Osmosis is a colligative property that works as follows:

The passage of the solvent to a solution or the passage of the solvent from a diluted solution to a more concentrated one occurs, through a semipermeable membrane.

Below we can see a fantasy color representation of the passage of pure solvent into a solution.

Osmosis process from pure solvent to solution

In the following case, we have the passage of the solvent (water molecules) from a diluted solution to a more concentrated one:

Osmosis process from the most dilute to the most concentrated solution

This is what happens, for example, when we put a carrot in a jar with a concentrated solution of water and salt. After approximately two days, it is noted that the carrot has less volume and a wrinkled appearance and shriveled up, because the water molecules in their cells are transferred to the brine, which is more concentrated. Water molecules pass through carrot cell membranes.

The idea of ​​this process is used in medicine, in hemodialysis. Although, the difference lies in the fact that in ordinary osmosis, through semipermeable membranes, only the solvent passes and the solute is retained. In hemodialysis, however, both the solvent (water) and the solute particles (among them, the toxic waste produced in our body) pass through the semipermeable membrane used.

The filtering membrane of the artificial kidney is formed by capillary filters, which are a set of thin tubes.

Dialysis is a slow process that has great therapeutic application, especially for patients with renal impairment, whether acute or chronic. Through the kidneys we eliminate toxic waste produced in the body, such as urea, nitrogen compounds and creatine. Those who have this problem, however, need to undergo hemodialysis sessions from 4 to 7 hours a day. And it can be for a person's lifetime if he doesn't get a transplant.

The process is as follows: the person's blood is pumped into a tube, which is lined with a semipermeable membrane (dialyzer membrane). This tube is immersed in a solution with blood plasma components. Thus, osmosis occurs: the particles of toxic waste present in the person's blood pass through the membrane and are eliminated. And the clean blood goes back to the person's body.

Diagram of a tube formed by a dialyzer membrane used in hemodialysis

Blood cells, proteins, and other blood components do not participate in osmosis because their particle size is larger than the membrane's pores.

hemodialysis scheme


By Jennifer Fogaça
Graduated in Chemistry

Source: Brazil School - https://brasilescola.uol.com.br/quimica/osmose-na-medicina-hemodialise.htm

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